1. Understand what really influences RPM
Locations aren't everything. Commercial traffic, a page that responds well to an intention and readable content often have more impact than a site overloaded with ads. RPM varies by country, niche, format, intent and season.
2. Use visible areas without breaking playback
The formats that perform best are often those that appear in a natural reading flow. This doesn't mean stacking blocks everywhere. A strong location above the fold, another in a long article and a last one at the end of the content are often enough to test properly.
3. Speed, confidence and compliance matter as much as placement
A slow or confusing page lowers advertising value as much as it harms the user. To monetize properly, you need stable pages, visible legal notices, healthy navigation and no artificial incentives to click. The best income over time comes from a clear site, not an aggressive site.